Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation

Abstract Background Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, a case was encountered in which the blood concentration of tacrolimus (TCR) at steady state increased after intravenous MTX adm...

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Autori principali:	Chiaki Inoue, Takehito Yamamoto, Hiroshi Miyata, Hiroshi Suzuki, Tappei Takada
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-12-01
Serie:	Journal of Pharmaceutical Health Care and Sciences
Soggetti:	Tacrolimus Methotrexate Hematopoietic stem cell transplantation Therapeutic drug monitoring
Accesso online:	https://doi.org/10.1186/s40780-023-00306-w
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