Never tear us a-PARP: Dealing with DNA lesions during mitosis
Tumors defective in homologous recombination (HR) are highly sensitive to poly ADP-ribose polymerase (PARP) inhibition, however the cell biological mechanisms underlying this synthetic lethality remain elusive. We recently identified that PARP inhibitor-induced DNA lesions persist until mitosis, sub...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis Group
2018-01-01
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| coleção: | Molecular & Cellular Oncology |
| Assuntos: | |
| Acesso em linha: | http://dx.doi.org/10.1080/23723556.2017.1382670 |
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