OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor

Abstract Ovo-like transcriptional repressor 1 (OVOL1) is a key mediator of epithelial lineage determination and mesenchymal–epithelial transition (MET). The cytokines transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMP) control the epithelial–mesenchymal plasticity (EMP) of can...

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書誌詳細

主要な著者:	Chuannan Fan, Qian Wang, Gerard van der Zon, Jiang Ren, Cedrick Agaser, Roderick C. Slieker, Prasanna Vasudevan Iyengar, Hailiang Mei, Peter ten Dijke
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Publishing Group 2022-04-01
シリーズ:	Signal Transduction and Targeted Therapy
オンライン･アクセス:	https://doi.org/10.1038/s41392-022-00944-w
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