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The Landscape of Pediatric High-Grade Gliomas: The Virtues and Pitfalls of Pre-Clinical Models

Pediatric high-grade gliomas (pHGG) are malignant and usually fatal central nervous system (CNS) WHO Grade 4 tumors. The majority of pHGG consist of diffuse midline gliomas (DMG), H3.3 or H3.1 K27 altered, or diffuse hemispheric gliomas (DHG) (H3.3 G34-mutant). Due to diffuse tumor infiltration of e...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Liam M. Furst, Enola M. Roussel, Ryan F. Leung, Ankita M. George, Sarah A. Best, James R. Whittle, Ron Firestein, Maree C. Faux, David D. Eisenstat
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2024-06-01
Rangatū:Biology
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2079-7737/13/6/424
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