The Landscape of Pediatric High-Grade Gliomas: The Virtues and Pitfalls of Pre-Clinical Models

Pediatric high-grade gliomas (pHGG) are malignant and usually fatal central nervous system (CNS) WHO Grade 4 tumors. The majority of pHGG consist of diffuse midline gliomas (DMG), H3.3 or H3.1 K27 altered, or diffuse hemispheric gliomas (DHG) (H3.3 G34-mutant). Due to diffuse tumor infiltration of e...

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Bibliografiske detaljer

Principais autores:	Liam M. Furst, Enola M. Roussel, Ryan F. Leung, Ankita M. George, Sarah A. Best, James R. Whittle, Ron Firestein, Maree C. Faux, David D. Eisenstat
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2024-06-01
Serier:	Biology
Fag:	pediatric high-grade gliomas diffuse midline gliomas diffuse hemispheric gliomas histone H3K27 altered histone H3G34 mutant in vitro models
Online adgang:	https://www.mdpi.com/2079-7737/13/6/424
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