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Multi-dimensional omics characterization in glioblastoma identifies the purity-associated pattern and prognostic gene signatures

Abstract Background The presence of tumor-associated stroma and tumor-infiltrated immune cells have been largely reported across glioblastomas. Tumor purity, defined as the proportion of tumor cells in the tumor, was associated with the genomic and clinicopathologic features of the tumor and may alt...

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Autori principali: Yi Xiong, Zujian Xiong, Hang Cao, Chang Li, Siyi Wanggou, Xuejun Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-01-01
Serie:Cancer Cell International
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Accesso online:https://doi.org/10.1186/s12935-020-1116-3
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