Multi-dimensional omics characterization in glioblastoma identifies the purity-associated pattern and prognostic gene signatures

Abstract Background The presence of tumor-associated stroma and tumor-infiltrated immune cells have been largely reported across glioblastomas. Tumor purity, defined as the proportion of tumor cells in the tumor, was associated with the genomic and clinicopathologic features of the tumor and may alt...

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Hauptverfasser:	Yi Xiong, Zujian Xiong, Hang Cao, Chang Li, Siyi Wanggou, Xuejun Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2020-01-01
Schriftenreihe:	Cancer Cell International
Schlagworte:	Tumor purity Glioblastoma Tumor immunity Tumor heterogeneity Tumor microenvironment
Online-Zugang:	https://doi.org/10.1186/s12935-020-1116-3
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