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Design and statistical optimization of an effervescent floating drug delivery system of theophylline using response surface methodology

The aim of this research was to formulate effervescent floating drug delivery systems of theophylline using different release retarding polymers such as ethyl cellulose, Eudragit® L100, xanthan gum and polyethylene oxide (PEO) N12K. Sodium bicarbonate was used as a gas generating agent. Direct compr...

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Principais autores: Srikanth Meka Venkata, Ee Li Chew, Sheshala Ravi
Formato: Artigo
Idioma:Inglês
Publicado: Sciendo 2016-03-01
Series:Acta Pharmaceutica
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Acceso en liña:https://doi.org/10.1515/acph-2016-0002
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