A self-adjuvant multiantigenic nanovaccines simultaneously activate the antiviral and antitumor immunity for the treatment of cancers

Abstract Background Tumor cell-derived extracellular vesicles (tEVs) have garnered significant attention as promising antigen delivery vehicles for the development of cancer vaccines. However, their practical applications are hindered by weak immunogenicity and inadequate lymph node targeting. In th...

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Bibliografische Detailangaben

Hauptverfasser:	Zhongjie Wang, Hanlin Chen, Ruiqi Ming, Weiwei Wang, Shujun Liu, Yuantian Jing, Zewei Yan, Guihong Lu, Li-Li Huang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-02-01
Schriftenreihe:	Journal of Nanobiotechnology
Schlagworte:	Cancer immunotherapy Multiantigenic nanovaccine Lymph node–tumor dual-targeting Low pH-responsive Antiviral and antitumor immunity
Online-Zugang:	https://doi.org/10.1186/s12951-025-03208-1
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