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A novel pThr217 tau monoclonal antibody reveals neuropathological heterogeneity in tauopathies

Abstract Tauopathies are a group of clinically and neuropathologically diverse neurodegenerative disorders defined by the abnormal aggregation of tau protein. While tau is normally soluble with limited secondary structure, pathological tau is characterized by hyperphosphorylation and assembly into f...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Giavanna Paterno, Brach M. Bell, Kimberly-Marie M. Gorion, Stephan Quintin, Stefan Prokop, Benoit I. Giasson
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-06-01
Saila:Scientific Reports
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1038/s41598-025-04291-y
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