IL-10 protects against OPC ferroptosis by regulating lipid reactive oxygen species levels post stroke

Accumulation of reactive oxygen species (ROS), especially on lipids, induces massive cell death in neurons and oligodendrocyte progenitor cells (OPCs) and causes severe neurologic deficits post stroke. While small compounds, such as deferoxamine, lipostatin-1, and ferrostatin-1, have been shown to b...

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Detalhes bibliográficos

Principais autores:	Weihua Wu, Zhaoli Luo, Danmin Shen, Ting Lan, Zhongnan Xiao, Meng Liu, Liye Hu, Tingting Sun, Yamei Wang, Jian-Nan Zhang, Chenguang Zhang, Peipei Wang, Yabin Lu, Fei Yang, Qian Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-02-01
Colecção:	Redox Biology
Assuntos:	Interleukin-10 Oligodendrocyte progenitor cells Lipid reactive oxygen species Ferroptosis Intracerebral hemorrhagic stroke
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S221323172300383X
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