The impact of the human DNA topoisomerase II C-terminal domain on activity.
Type II DNA topoisomerases (topos) are essential enzymes needed for the resolution of topological problems that occur during DNA metabolic processes. Topos carry out an ATP-dependent strand passage reaction whereby one double helix is passed through a transient break in another. Humans have two topo...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2008-03-01
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| Серии: | PLoS ONE |
| Online-ссылка: | http://europepmc.org/articles/PMC2262138?pdf=render |
| Метки: |
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