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DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage

BackgroundCantharidin (CTD) extracted from the traditional Chinese medicine Mylabris has significant therapeutic effects on various tumors. However, the high toxicity of CTD can cause serious liver damage, although the related molecular mechanisms remain unclear.MethodsIn this study, we established...

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Hlavní autoři: Wenchao Tang, Yue Pan, Can Zhu, Didong Lou, Fang Peng, Qin Shi, Yuanyuan Xiao
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-11-01
Edice:Frontiers in Pharmacology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fphar.2024.1480512/full
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