Synthesis and anti-prion aggregation activity of acylthiosemicarbazide analogues
Prions are infectious protein particles known to cause prion diseases. The biochemical entity of the pathogen is the misfolded prion protein (PrPSc) that forms insoluble amyloids to impair brain function. PrPSc interacts with the non-pathogenic, cellular prion protein (PrPC) and facilitates conversi...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis Group
2023-12-01
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| Seri Bilgileri: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Konular: | |
| Online Erişim: | https://www.tandfonline.com/doi/10.1080/14756366.2023.2191164 |
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