Codice QR

Synthesis and anti-prion aggregation activity of acylthiosemicarbazide analogues

Prions are infectious protein particles known to cause prion diseases. The biochemical entity of the pathogen is the misfolded prion protein (PrPSc) that forms insoluble amyloids to impair brain function. PrPSc interacts with the non-pathogenic, cellular prion protein (PrPC) and facilitates conversi...

Descrizione completa

Salvato in:
Autori principali: Dong Hwan Kim, Jaehyeon Kim, Hakmin Lee, Dongyun Lee, So Myoung Im, Ye Eun Kim, Miryeong Yoo, Yong-Pil Cheon, Jason C. Bartz, Young-Jin Son, Eun-Kyoung Choi, Yong-Sun Kim, Jae-Ho Jeon, Hyo Shin Kim, Sungeun Lee, Chongsuk Ryou, Tae-gyu Nam
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2023-12-01
Serie:Journal of Enzyme Inhibition and Medicinal Chemistry
Soggetti:
Prion disease Creutzfeldt–Jakob disease
prion aggregation formation assay
acylthiosemicarbazide
Accesso online:https://www.tandfonline.com/doi/10.1080/14756366.2023.2191164
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi