Innate and Adaptive Responses of Intratumoral Immunotherapy with Endosomal Toll-Like Receptor Agonists

Toll-like receptors (TLRs) are natural initial triggers of innate and adaptive immune responses. With the advent of cancer immunotherapy, nucleic acids engineered as ligands of endosomal TLRs have been investigated for the treatment of solid tumors. Despite promising results, their systemic administ...

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Bibliografski detalji

Glavni autori:	Fernando Torres Andón, Sergio Leon, Aldo Ummarino, Esther Redin, Paola Allavena, Diego Serrano, Clément Anfray, Alfonso Calvo
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-07-01
Serija:	Biomedicines
Teme:	toll-like receptors TLR agonists intratumoral administration antitumoral immunotherapy tumor associated macrophages
Online pristup:	https://www.mdpi.com/2227-9059/10/7/1590
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