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Invention and characterization of a systemically administered, attenuated and killed bacteria-based multiple immune receptor agonist for anti-tumor immunotherapy

Activation of immune receptors, such as Toll-like (TLR), NOD-like (NLR) and Stimulator of Interferon Genes (STING) is critical for efficient innate and adaptive immunity. Gram-negative bacteria (G-NB) contain multiple TLR, NOD and STING agonists. Potential utility of G-NB for cancer immunotherapy is...

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Bibliografiska uppgifter
Huvudupphov: Michael J. Newman
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2024-11-01
Serie:Frontiers in Immunology
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Länkar:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1462221/full
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