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Integrated analysis of circulating cell free nucleic acids for cancer genotyping and immune phenotyping of tumor microenvironment

The circulating cell-free nucleic acids (ccfNAs) consist of a heterogenous cocktail of both single (ssNA) and double-stranded (dsNA) nucleic acids. These ccfNAs are secreted into the blood circulation by both healthy and malignant cells via various mechanisms including apoptosis, necrosis, and activ...

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Auteurs principaux: Muskan Chaddha, Hemlata Rai, Ritu Gupta, Deepshi Thakral
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2023-04-01
Collection:Frontiers in Genetics
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fgene.2023.1138625/full
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