Binding selectivity analysis of AURKs inhibitors through molecular dynamics simulation studies.

Aurora kinases (AURKs) have been identified as promising biological targets for the treatment of cancer. In this study, molecular dynamics simulations were employed to investigate the binding selectivity of three inhibitors (HPM, MPY, and VX6) towards AURKA and AURKB by predicting their binding free...

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מידע ביבליוגרפי

Principais autores:	Rima D Alharthy, Ghulam Fatima, Numan Yousaf, Muhammad Shaheen Iqbal, Sadia Sattar, Abdullah R Alanzi, Ijaz Ali, Muhammad Muddassar
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science (PLoS) 2023-01-01
סדרה:	PLoS ONE
גישה מקוונת:	https://doi.org/10.1371/journal.pone.0295741
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!