In vivo induction of membrane damage by β-amyloid peptide oligomers

Abstract Exposure to the β-amyloid peptide (Aβ) is toxic to neurons and other cell types, but the mechanism(s) involved are still unresolved. Synthetic Aβ oligomers can induce ion-permeable pores in synthetic membranes, but whether this ability to damage membranes plays a role in the ability of Aβ o...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Carl Julien, Colson Tomberlin, Christine M. Roberts, Aumbreen Akram, Gretchen H. Stein, Michael A. Silverman, Christopher D. Link
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2018-11-01
Цуврал:	Acta Neuropathologica Communications
Нөхцлүүд:	Alzheimer’s disease β-amyloid Tau Caenorhabditis elegans Pore-forming toxin
Онлайн хандалт:	http://link.springer.com/article/10.1186/s40478-018-0634-x
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!