Inactivity-induced NR4A3 downregulation in human skeletal muscle affects glucose metabolism and translation: Insights from in vitro analysis

Objective: Physical activity promotes health, whereas inactivity is associated with metabolic impairment. The transcription factor nuclear receptor subfamily 4 group A member 3 (NR4A3) is a pleiotropic regulator of skeletal muscle exercise adaptation and metabolism. However, the consequence of lower...

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Κύριοι συγγραφείς:	Jonathon A.B. Smith, Brendan M. Gabriel, Aidan J. Brady, Ahmed M. Abdelmoez, Mladen Savikj, Shane C. Wright, Stefania Koutsilieri, Romain Barrès, Volker M. Lauschke, Anna Krook, Juleen R. Zierath, Nicolas J. Pillon
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2025-09-01
Σειρά:	Molecular Metabolism
Θέματα:	Skeletal muscle Inactivity Metabolism Mitochondria Protein synthesis
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2212877825001073
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