Identification of novel amrR deletions as meropenem resistance mechanisms in clinical Burkholderia pseudomallei isolates

ABSTRACT Burkholderia pseudomallei, an environmental bacterium, is the causative agent of melioidosis, a potentially fatal infectious disease predominantly found in tropical regions. Despite the bacterium’s intrinsic resistance to numerous antibiotics, the antibiotic resistance mechanisms remain poo...

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Hlavní autoři:	Supichaya Nimnuan-ngam, Shirley Yi Fen Hii, Rathanin Seng, Natnaree Saiprom, Sarunporn Tandhavanant, T. Eoin West, Narisara Chantratita
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-05-01
Edice:	Microbiology Spectrum
Témata:	amrR mutation AmrAB-OprA efflux pump drug resistance melioidosis meropenem Burkholderia pseudomallei
On-line přístup:	https://journals.asm.org/doi/10.1128/spectrum.01936-24
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