Identification of novel amrR deletions as meropenem resistance mechanisms in clinical Burkholderia pseudomallei isolates

ABSTRACT Burkholderia pseudomallei, an environmental bacterium, is the causative agent of melioidosis, a potentially fatal infectious disease predominantly found in tropical regions. Despite the bacterium’s intrinsic resistance to numerous antibiotics, the antibiotic resistance mechanisms remain poo...

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Egile Nagusiak: Supichaya Nimnuan-ngam, Shirley Yi Fen Hii, Rathanin Seng, Natnaree Saiprom, Sarunporn Tandhavanant, T. Eoin West, Narisara Chantratita
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2025-05-01
Saila:Microbiology Spectrum
Gaiak:
amrR mutation
AmrAB-OprA efflux pump
drug resistance
melioidosis
meropenem
Burkholderia pseudomallei
Sarrera elektronikoa:https://journals.asm.org/doi/10.1128/spectrum.01936-24
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