HspBP1 is a dual function regulatory protein that controls both DNA repair and apoptosis in breast cancer cells

Abstract The Hsp70-binding protein 1 (HspBP1) belongs to a family of co-chaperones that regulate Hsp70 activity and whose biological significance is not well understood. In the present study, we show that when HspBP1 is either knocked down or overexpressed in BRCA1-proficient breast cancer cells, th...

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Detalhes bibliográficos

Principais autores:	Cha Kyung Youn, Jung-Hee Lee, Gurusamy Hariharasudhan, Hong Beum Kim, Jeeho Kim, Sumi Lee, Sung-Chul Lim, Sang-Pil Yoon, Sang-Gon Park, In-Youb Chang, Ho Jin You
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2022-04-01
coleção:	Cell Death and Disease
Acesso em linha:	https://doi.org/10.1038/s41419-022-04766-0
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