Golgi Fragmentation in Amyotrophic Lateral Sclerosis, an Overview of Possible Triggers and Consequences

Amyotrophic Lateral Sclerosis (ALS) is an invariably fatal neurodegenerative disorder, which specifically targets motor neurons in the brain, brain stem and spinal cord. Whilst the etiology of ALS remains unknown, fragmentation of the Golgi apparatus is detected in ALS patient motor neurons and in a...

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Autors principals:	Vinod eSundaramoorthy, Jessica M Sultana, Julie D Atkin
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2015-10-01
Col·lecció:	Frontiers in Neuroscience
Matèries:	Amyotrophic Lateral Sclerosis er stress Axonal degeneration Golgi fragmentation secretory trafficking inhibition autophagy dysfunction
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00400/full
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