Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom

Mutations in the gene encoding N-myc downstream-regulated gene-1 (NDRG1) lead to truncations of the encoded protein and are associated with an autosomal recessive demyelinating neuropathy—hereditary motor and sensory neuropathy-Lom. NDRG1 protein is highly expressed in peripheral nerve and is locali...

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Bibliografski detalji

Glavni autori:	Philipp Berger, Erich E. Sirkowski, Steven S. Scherer, Ueli Suter
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2004-11-01
Serija:	Neurobiology of Disease
Teme:	Neuropathy Oligodendrocytes Myelin Charcot-Marie-Tooth disease CMT Schwann cells
Online pristup:	http://www.sciencedirect.com/science/article/pii/S096999610400155X
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