Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system
Myelination is a biosynthetically demanding process in which mTORC1, the gatekeeper of anabolism, occupies a privileged regulatory position. We have shown previously that loss of mTORC1 function in Schwann cells (SCs) hampers myelination. Here, we genetically disrupted key inhibitory components upst...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
eLife Sciences Publications Ltd
2017-09-01
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| Saila: | eLife |
| Gaiak: | |
| Sarrera elektronikoa: | https://elifesciences.org/articles/29241 |
| Etiketak: |
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