Proteome-wide signatures of function in highly diverged intrinsically disordered regions

Intrinsically disordered regions make up a large part of the proteome, but the sequence-to-function relationship in these regions is poorly understood, in part because the primary amino acid sequences of these regions are poorly conserved in alignments. Here we use an evolutionary approach to detect...

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Detalhes bibliográficos

Principais autores:	Taraneh Zarin, Bob Strome, Alex N Nguyen Ba, Simon Alberti, Julie D Forman-Kay, Alan M Moses
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2019-07-01
coleção:	eLife
Assuntos:	evolution purifying selection clustering mitochondial targeting signals unstructured protein molecular features
Acesso em linha:	https://elifesciences.org/articles/46883
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