CCR-CCL axes as key upstream influencers of pancreatic ductal adenocarcinoma: CCR2–CCL2, CCR5–CCL5, CCR4–CCL17/22, CCR6–CCL20, CCR7–CCL19/21
PDAC remains one of the most lethal malignancies, characterized by a highly desmoplastic ECM that promotes an immunosuppressive signaling network and dampens the effectiveness of traditional therapies. Among the several key contributors to its immune evasion pathways are chemokine signaling axes, wh...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Frontiers Media S.A.
2026-01-01
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| Serie: | Frontiers in Immunology |
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| Accesso online: | https://www.frontiersin.org/articles/10.3389/fimmu.2026.1713123/full |
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