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Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies

Chimeric-antigen-receptor (CAR) T-cell therapy for CD19-expressing B-cell malignancies is already widely adopted in clinical practice. On the other hand, the development of CAR-T-cell therapy for T-cell malignancies is in its nascent stage. One of the potential targets is CD26, to which we have deve...

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Principais autores: Eiji Kobayashi, Yusuke Kamihara, Miho Arai, Akinori Wada, Shohei Kikuchi, Ryo Hatano, Noriaki Iwao, Takeshi Susukida, Tatsuhiko Ozawa, Yuichi Adachi, Hiroyuki Kishi, Nam H. Dang, Taketo Yamada, Yoshihiro Hayakawa, Chikao Morimoto, Tsutomu Sato
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-08-01
Serier:Cells
Fag:
CD26
CAR-T
T-cell malignancies
third-generation
fratricide
Online adgang:https://www.mdpi.com/2073-4409/12/16/2059
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