Genetic Correlates of Synergy Mechanisms of Daptomycin Plus Fosfomycin in Daptomycin-Susceptible and -Resistant Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA)

This study elucidates potential genetic determinants and mechanisms involved in the synergistic effects of daptomycin (DAP) + fosfomycin (FOF) combination therapy. Among 33 clinically derived DAP-susceptible (S)/DAP-resistant (R) isogenic strain pairs, mutations in the <i>mprF</i> gene occurred in 3...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Warren E. Rose, Selvi C. Ersoy, Wessam Abdelhady, Alan R. Dominguez, Jedidiah Ndam Muyah Manna, Jorge N. Artaza, Reetakshi Mishra, Ahmed M. Elsayed, Richard A. Proctor, Sarah L. Baines, Benjamin P. Howden, Nagendra N. Mishra
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-06-01
coleção:	Microorganisms
Assuntos:	MRSA daptomycin fosfomycin combination therapy transcriptomics
Acesso em linha:	https://www.mdpi.com/2076-2607/13/7/1532
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!