Genetic Correlates of Synergy Mechanisms of Daptomycin Plus Fosfomycin in Daptomycin-Susceptible and -Resistant Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA)

This study elucidates potential genetic determinants and mechanisms involved in the synergistic effects of daptomycin (DAP) + fosfomycin (FOF) combination therapy. Among 33 clinically derived DAP-susceptible (S)/DAP-resistant (R) isogenic strain pairs, mutations in the <i>mprF</i> gene occurred in 3...

Descrición completa

Detalles Bibliográficos

Principais autores:	Warren E. Rose, Selvi C. Ersoy, Wessam Abdelhady, Alan R. Dominguez, Jedidiah Ndam Muyah Manna, Jorge N. Artaza, Reetakshi Mishra, Ahmed M. Elsayed, Richard A. Proctor, Sarah L. Baines, Benjamin P. Howden, Nagendra N. Mishra
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2025-06-01
Series:	Microorganisms
Assuntos:	MRSA daptomycin fosfomycin combination therapy transcriptomics
Acceso en liña:	https://www.mdpi.com/2076-2607/13/7/1532
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!