Identification of spastic ataxia-related proteins via comparative proteomic analysis of the cerebellum of conditional Ankfy1 knockout mice

Abstract Ankyrin repeat and FYVE domain containing 1 (ANKFY1) is an indispensable protein in the development of cerebellar Purkinje cells. Our preliminary study revealed that its absence caused progressive spastic ataxia, accompanied by the loss of Purkinje cells in mice. Here, we generated Ankfy1-f...

詳細記述

書誌詳細

主要な著者:	Rong Fu, Man Ding, Tong Yin, Linlin Zheng, Yue Liu, Hang Yu, Rumeng Zhou, Zuneng Lu
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2025-07-01
シリーズ:	Scientific Reports
主題:	Ankfy1 Purkinje cell Spastic ataxia Data-independent acquisition
オンライン･アクセス:	https://doi.org/10.1038/s41598-025-06398-8
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!