A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease.

Chemokines are small proteins that promote leukocyte migration during development, infection, and inflammation. We and others isolated the unique chemokine CCL21, a potent chemo-attractant for naïve T-cells, naïve B-cells, and immature dendritic cells. CCL21 has a 37 amino acid carboxy terminal exte...

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Principais autores:	Maegan L Capitano, Aruna Jaiswal, Hal E Broxmeyer, Yilianys Pride, Sarah Glover, Fatemah G Amlashi, Austin Kirby, Gayathri Srinivasan, Elizabeth A Williamson, Daniel Mais, Robert Hromas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2021-01-01
coleção:	PLoS ONE
Acesso em linha:	https://doi.org/10.1371/journal.pone.0252805
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