Alloantigen-induced unresponsiveness in cord blood T lymphocytes is associated with defective activation of Ras

Human umbilical cord blood T lymphocytes (CBTL) respond to primary allostimulation but they do not proliferate upon rechallenge with alloantigen. Using PKH-26-labeled cells created a proliferative block that was observed only in CBTL that have divided during primary stimulation (PKH-26(dim)) but not...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Porcu, Pierluigi, Gaddy, Jay, Broxmeyer, Hal E.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1998
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539773/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4538
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