The Etiology and Molecular Mechanism Underlying Smooth Muscle Phenotype Switching in Intimal Hyperplasia of Vein Graft and the Regulatory Role of microRNAs
Mounting evidence suggests that the phenotypic transformation of venous smooth muscle cells (SMCs) from differentiated (contractile) to dedifferentiated (proliferative and migratory) phenotypes causes excessive proliferation and further migration to the intima leading to intimal hyperplasia, which r...
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| Principais autores: | , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Frontiers Media S.A.
2022-07-01
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| 丛编: | Frontiers in Cardiovascular Medicine |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.935054/full |
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