The Etiology and Molecular Mechanism Underlying Smooth Muscle Phenotype Switching in Intimal Hyperplasia of Vein Graft and the Regulatory Role of microRNAs

Mounting evidence suggests that the phenotypic transformation of venous smooth muscle cells (SMCs) from differentiated (contractile) to dedifferentiated (proliferative and migratory) phenotypes causes excessive proliferation and further migration to the intima leading to intimal hyperplasia, which r...

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Bibliografische Detailangaben

Hauptverfasser:	Dengshen Zhang, Yiran Cao, Daxing Liu, Jian Zhang, Yingqiang Guo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2022-07-01
Schriftenreihe:	Frontiers in Cardiovascular Medicine
Schlagworte:	miRNAs VSMCs phenotypic transformation intimal hyperplasia vein graft
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fcvm.2022.935054/full
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