Human spindle-shaped urine-derived stem cell exosomes alleviate severe fatty liver ischemia–reperfusion injury by inhibiting ferroptosis via GPX4

Abstract Background Severe hepatic steatosis can exacerbate Ischemia–reperfusion injury (IRI), potentially leading to early graft dysfunction and primary non-function. In this study, we investigated the heterogeneity of different subpopulations of Urine-derived stem cells (USCs) to explore the most...

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Detalhes bibliográficos

Principais autores:	Shangheng Shi, Cunle Zhu, Shangxuan Shi, Xinqiang Li, Imran Muhammad, Qingguo Xu, Xinwei Li, Ziyin Zhao, Huan Liu, Guangming Fu, Meiying Song, Xijian Huang, Feng Wang, Jinzhen Cai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-02-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Urine-derived stem cells Heterogeneity Exosomes Ferroptosis Ischemia–reperfusion injury Fatty liver
Acesso em linha:	https://doi.org/10.1186/s13287-025-04202-y
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