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Iron and Copper Intracellular Chelation as an Anticancer Drug Strategy

A very promising direction in the development of anticancer drugs is inhibiting the molecular pathways that keep cancer cells alive and able to metastasize. Copper and iron are two essential metals that play significant roles in the rapid proliferation of cancer cells and several chelators have been...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Kavita Gaur, Alexandra M. Vázquez-Salgado, Geraldo Duran-Camacho, Irivette Dominguez-Martinez, Josué A. Benjamín-Rivera, Lauren Fernández-Vega, Lesly Carmona Sarabia, Angelys Cruz García, Felipe Pérez-Deliz, José A. Méndez Román, Melissa Vega-Cartagena, Sergio A. Loza-Rosas, Xaymara Rodriguez Acevedo, Arthur D. Tinoco
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2018-11-01
Schriftenreihe:Inorganics
Schlagworte:
copper and iron chelators in cancer
transmetalation
metastasis
angiogenesis
metallomics
Online-Zugang:https://www.mdpi.com/2304-6740/6/4/126
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