Age, vascular disease, and Alzheimer’s disease pathologies in amyloid negative elderly adults

Abstract Background We recently reported that CSF phosphorylated tau (p-Tau181) relative to Aβ40 (CSF p-Tau/Aβ40 ratio) was less noisy and increased associations with Alzheimer’s disease (AD) biomarkers compared to CSF p-Tau181 alone. While elevations of CSF p-Tau/Aβ40 can occur in amyloid-β (Aβ) ne...

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Autors principals:	Tengfei Guo, Susan M. Landau, William J. Jagust, for the Alzheimer’s Disease Neuroimaging Initiative
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2021-10-01
Col·lecció:	Alzheimer’s Research & Therapy
Matèries:	Alzheimer’s disease Amyloid negative CSF p-Tau Hippocampal atrophy Hypometabolism Vascular disease
Accés en línia:	https://doi.org/10.1186/s13195-021-00913-5
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