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The A4 study: β‐amyloid and cognition in 4432 cognitively unimpaired adults

Abstract Objective To clarify the preclinical stage of Alzheimer’s disease by estimating when β‐amyloid accumulation first becomes associated with changes in cognition. Methods Here we studied a large group (N = 4432) of cognitively unimpaired individuals who were screened for inclusion in the A4 tr...

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Principais autores: Philip S. Insel, Michael C. Donohue, Reisa Sperling, Oskar Hansson, Niklas Mattsson‐Carlgren
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-05-01
coleção:Annals of Clinical and Translational Neurology
Acesso em linha:https://doi.org/10.1002/acn3.51048
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