Early‐life antibiotic exposure aggravates hepatic steatosis through enhanced endotoxemia and lipotoxic effects driven by gut Parabacteroides

Abstract Compelling evidence supports a link between early‐life gut microbiota and the metabolic outcomes in later life. Using an early‐life antibiotic exposure model in BALB/c mice, we investigated the life‐course impact of prenatal and/or postnatal antibiotic exposures on the gut microbiome of off...

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Autori principali:	Xi Zhang, Darren Chak Lun Chan, Jie Zhu, Daniel Zhen Ye Sin, Ye Peng, Matthew Kwok Leong Wong, Wenyi Zhu, Yee Tsui, Andrea M. Haqq, Joseph Y. Ting, Anita Kozyrskyj, Francis Ka Leung Chan, Siew Chien Ng, Hein Min Tun
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2025-03-01
Serie:	MedComm
Soggetti:	antibiotics early life gut microbiota lipotoxicity metabolic dysfunction‐associated steatotic liver disease
Accesso online:	https://doi.org/10.1002/mco2.70104
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