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CD56bright NK cells are negatively associated with antibody response to vaccination in people with multiple sclerosis on B‐cell‐depleting therapy

Abstract Objectives We sought to identify determinants of vaccine response in people with multiple sclerosis (pwMS) receiving B‐cell‐depleting therapies. Methods This was a prospective single‐centre cohort study (ACTRN12623001249640). Peripheral blood samples were collected from pwMS receiving ocrel...

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Kaydedildi:
Asıl Yazarlar: Griffith B Perkins, Christopher M Hope, Cheng Sheng Chai, Matthew J Tunbridge, Sebastian Sterling, Kevin Webb, Joey Yap, Arthur Eng Lip Yeow, Makutiro G Masavuli, Jacqueline Scaffidi, James D Zuiani, Anouschka Akerman, Anupriya Aggarwal, Vanessa Milogiannakis, Matthew B Roberts, Plinio R Hurtado, Stuart Turville, Branka Grubor‐Bauk, Simon C Barry, Janakan Ravindran, Patrick Toby Coates, Pravin Hissaria
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2026-02-01
Seri Bilgileri:Clinical & Translational Immunology
Konular:
B‐cell depletion
CD56bright NK cells
multiple sclerosis
vaccination
virus neutralisation
Online Erişim:https://doi.org/10.1002/cti2.70079
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