Controversies and insights into PTBP1-related astrocyte-neuron transdifferentiation: neuronal regeneration strategies for Parkinson’s and Alzheimer’s disease

Abstract Promising therapeutic strategies are being explored to replace or regenerate the neuronal populations that are lost in patients with neurodegenerative disorders. Several research groups have attempted direct reprogramming of astrocytes into neurons by manipulating the expression of polypyri...

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Bibliografiske detaljer

Principais autores:	Simon McDowall, Vaishali Bagda, Stuart Hodgetts, Frank Mastaglia, Dunhui Li
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2024-12-01
Serier:	Translational Neurodegeneration
Fag:	Neuronal regeneration, Astrocyte-neuron reprogramming, Astrocyte heterogeneity, Therapeutic strategies
Online adgang:	https://doi.org/10.1186/s40035-024-00450-9
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