Whole exome sequencing identifies a novel FANCD2 gene splice site mutation associated with disease progression in chronic myeloid leukemia: Implication in targeted therapy of advanced phase CML

Chronic Myeloid Leukemia (CML) is caused by BCR-ABL1 fusion oncogene resulted due to translocation between chromosomes 9 and 22. Tyrosine Kinase Inhibitors (TKIs) have significantly improved clinical outcome of chronic phase-Chronic Myeloid Leukemia (CP-CML). Nonetheless, approximately one third of...

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Detalhes bibliográficos

Principais autores:	Muhammad Absar, Amer Mahmood, Tanveer Akhtar, Sulman Basit, Khushnooda Ramzan, Abid Jameel, Sibtain Afzal, Anhar Ullah, Kulsoom Qureshi, Nawaf Alanazi, Zafar Iqbal Medical Oncology Unit, HMC, Peshawar, Pakistan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	University of Karachi 2020-07-01
coleção:	Pakistan Journal of Pharmaceutical Sciences
Acesso em linha:	https://pjps.pk/single-article?id=cmrvxrq3o0602o08e60aj3ag5
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