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Tensile force promotes osteogenic differentiation via ephrinB2-EphB4 signaling pathway in orthodontic tooth movement

Abstract Objective To investigating whether osteogenic differentiation of osteoblasts promoted by tension force (TF) is mediated by ephrinB2-EphB4 signaling. Methods TF was applied to MC3T3-E1 cells, then CCK-8 and live/dead staining were used to detect cell proliferation. Levels of osteogenic diffe...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Hang Yu, Xiaoxi Wei, Huan Jiang, Huichuan Qi, Yi Zhang, Min Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-01-01
Schriftenreihe:BMC Oral Health
Schlagworte:
Orthodontic tooth movement
Tensile force
Osteogenic differentiation
ephrinB2-EphB4
ERK1/2
Online-Zugang:https://doi.org/10.1186/s12903-025-05491-8
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