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Synthetic α-Conotoxin Mutants as Probes for Studying Nicotinic Acetylcholine Receptors and in the Development of Novel Drug Leads

α-Conotoxins are peptide neurotoxins isolated from venomous marine cone snails that are potent and selective antagonists for different subtypes of nicotinic acetylcholine receptors (nAChRs). As such, they are valuable probes for dissecting the role that nAChRs play in nervous system function. In rec...

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Autor principal: Christopher J. Armishaw
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2010-06-01
Colecção:Toxins
Assuntos:
Acesso em linha:http://www.mdpi.com/2072-6651/2/6/1471/
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