Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma

Abstract Background Glaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells. Recent work in animal models suggests that a critical neuroinflammatory event damages retinal ganglion cell axons in the optic nerve head during ocular hypertensive injury. We previously...

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Hlavní autoři:	Pete A. Williams, Catherine E. Braine, Krishnakumar Kizhatil, Nicole E. Foxworth, Nicholas G. Tolman, Jeffrey M. Harder, Rebecca A. Scott, Gregory L. Sousa, Alyssa Panitch, Gareth R. Howell, Simon W. M. John
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2019-01-01
Edice:	Molecular Neurodegeneration
Témata:	Glaucoma Retinal ganglion cell Optic nerve Monocyte Vascular leakage Extravasation
On-line přístup:	http://link.springer.com/article/10.1186/s13024-018-0303-3
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