Steroidogenesis and early response gene expression in MA-10 Leydig tumor cells following heterologous receptor down-regulation and cellular desensitization

The Leydig tumor cell line, MA-10, expresses the luteinizing hormone receptor, a G protein-coupled receptor that, when activated with luteinizing hormone or chorionic gonadotropin (CG), stimulates cAMP production and subsequent steroidogenesis, notably progesterone. These cells also respond to epide...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Tsuey-Ming Chen, Frank S. Czerwiec, David Puett
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2016-03-01
Schriftenreihe:	Biochemistry and Biophysics Reports
Schlagworte:	Cellular desensitization Early response genes Epidermal growth factor and receptor Human chorionic gonadotropin and receptor MA-10 cells Steroidogenesis
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2405580816000066
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