Steroidogenesis and early response gene expression in MA-10 Leydig tumor cells following heterologous receptor down-regulation and cellular desensitization

The Leydig tumor cell line, MA-10, expresses the luteinizing hormone receptor, a G protein-coupled receptor that, when activated with luteinizing hormone or chorionic gonadotropin (CG), stimulates cAMP production and subsequent steroidogenesis, notably progesterone. These cells also respond to epide...

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Autori principali:	Tsuey-Ming Chen, Frank S. Czerwiec, David Puett
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2016-03-01
Serie:	Biochemistry and Biophysics Reports
Soggetti:	Cellular desensitization Early response genes Epidermal growth factor and receptor Human chorionic gonadotropin and receptor MA-10 cells Steroidogenesis
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2405580816000066
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